REAL INTAKE AND PROVISION WITH VITAMINS AND CALCIUM IN OSTEOPOROSIS: ASSESSMENT BY MEASURING INTAKE AND PLASMA CONCENTRATIONS

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Abstract

Aim:  To assess the providing an organism with vitamins (А, В2, С, Е), β-carotene, and calcium in osteoporosis patients by measuring their intake and plasma concentrations. Materials and methods: 108 pairs “osteoporosis patient – healthy volunteer” aged 64.29±9.73 years were formed using a “case-control” method. Real intake of vitamins and calcium was studied defining the frequency of food taking for a month using questionnaire method. Daily intake of vitamins А, В2, С, Е, β-carotene, and calcium was calculated based on the analysis of the frequency of food taking. Among the basic group, using randomized method, 60% of osteoporosis patients were selected who underwent definition of plasma levels of vitamins А, В2, С, and Е. The same study was performed in 60 control volunteers. Results: Correlation of the intake of vitamins A, C, and β-carotene with their plasma levels wasn’t noted. It may reveal an increased need in these nutrients in osteoporosis. According to the calcium intake, every osteoporosis patient can be attributed to a population category with deep insufficiency of calcium intake (less than 500 mg a day). Conclusion: The data obtained need further investigation and, first of all, in clinical and biochemical fields (enzymatic non-provision for calcium uptake, clinical manifestations of insufficient provision with nutrients). Solution of these problems would enable regulation of food intake concerning calcium uptake in osteoporosis.

About the authors

V. N. Khodyrev

Ural State Medical University; 3 Repina ul., Yekaterinburg, Sverdlovskaya oblast’, 620028, Russian Federation

Author for correspondence.
Email: vitalykhodyrev@yandex.ru
MD, PhD, Assistant of the Chair of Family Medicine, Ural State Medical University Russian Federation

O. M. Lesnyak

Ural State Medical University; 3 Repina ul., Yekaterinburg, Sverdlovskaya oblast’, 620028, Russian Federation

Email: fake@neicon.ru
MD, PhD, Professor, Head of the Chair of Family Medicine, Ural State Medical University Russian Federation

A. N. Martinchik

Scientific Research Institute of Nutrition; 2/14 Ust’inskiy proezd, Moscow, 109240, Russian Federation

Email: fake@neicon.ru

MD, PhD, Professor, Leading researcher, Laboratory of Nourishment Epidemiology, Scientific Research Institute of Nutrition.

Russian Federation

D. M. Maksimov

Ural State Medical University; 3 Repina ul., Yekaterinburg, Sverdlovskaya oblast’, 620028, Russian Federation

Email: fake@neicon.ru
PhD, Assistant of the Chair of Family Medicine, Ural State Medical University Russian Federation

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Copyright (c) 2014 Khodyrev V.N., Lesnyak O.M., Martinchik A.N., Maksimov D.M.

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