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The article presents a case of a very rare disorder – generalized eruptive keratoacanthoma of Grzybowski in a woman aged 82 years old. The disease is characterized by sudden emergence of hundreds or thousands of neoplasms (2–5 cm in diameters) rapidly spreading throughout the body skin. It is frequently associated with internistic cancer. In this case, generalized eruptive keratoacanthoma of Grzybowski was diagnosed 4 years after the disease onset. The authors emphasize the role of proper diagnosis and treatment of this pathology. Aromatic retinoids were highly effective in the therapy of generalized eruptive keratoacanthoma of Grzybowski.

About the authors

V. A. Molochkov

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

MD, PhD, Professor, Head of the Dermatovenereology and Dermato-Oncology Department Russian Federation

Zh. S. Kuntsevich

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Author for correspondence.
MD, PhD, Associate Professor, Dermatovenereology and Dermato-Oncology Department Russian Federation

M. A. Bobrov

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Research Associate, Department of Pathological Anatomy Russian Federation

S. A. Dibirova

I.M. Sechenov First Moscow State Medical University; 8/2 Trubetskaya ul., Moscow, 119991, Russian Federation


Fellow, Department of Skin and Venereal Diseases, Institute for Professional Education 


Russian Federation


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Copyright (c) 2014 Molochkov V.A., Kuntsevich Z.S., Bobrov M.A., Dibirova S.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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