COMPARISON OF DIFFERENT METHODS OF PHYSIOTHERAPY TREATMENT IN THE MANAGEMENT OF PRIMARY OPEN-ANGLE GLAUCOMA

Cover Page


Cite item

Full Text

Abstract

Background: Therapeutic action of physical therapy aims at the recovery of conductibility of optic tracts, improvement of microcirculation and hemodynamics, stimulation of regulatory brain structures and improvement of psycho-neurological status of patients. 

Aim: To assess efficacy of transcranial magnetic therapy, contemporary transcranial magnetic therapy/electrostimulation and magnetic sympathocorrection in the treatment of primary open-angle glaucoma. 

Materials and methods: 397 patients (634 eyes), aged 58–76 years, with verified diagnosis of stage I, II or III primary open-angle glaucoma, received transcranial magnetic therapy (group 1, 182 eyes), contemporary transcranial magnetic  herapy/electrostimulation (group 2, 258 eyes) and magnetic sympathocorrection (group 3, 194 eyes). All patients underwent routine ophthalmological examination, visual evoked potential recording and assessment of ocular circulation. 

Results: In patients with initial stage of glaucoma, most prominent changes of electrophysiological parameters was demonstrated in the group 2: visual evoked potential amplitude increased from 8.4 ± 0.4 to 11.3 ± 0.2 mcV, latency decreased from 77.6 ± 1.3 to 70.4 ± 2.1 ms. Maximal improvement of ocular circulation (decrease of resistance index of posterior short ciliary arteries from 0.69 ± 0.02 to 0.51 ± 0.03) was registered in the group 3. In patients with evolved glaucoma (stage II), significant increase of P100 amplitude of visual evoked potentials (from 7.5 ± 0.2 to 9.8 ± 0.3 mcV) was found in the group 2; latency period decreased from 84.6 ± 1.5 to 74.8 ± 2.1 ms. In stage II glaucoma patients, prominent increase of systolic blood velocity was demonstrated in groups 3 and 2: from 11.26 ± 0.8 to 13.64 ± 0.63 cm/s and from 10.5 ± 0.2 to 13.9 ± 0.7 cm/s, respectively. Resistance index decreased from 0.76 ± 0.05 to 0.52 ± 0.02 and from 0.75 ± 0.02 to 0.65 ± 0.02 in groups 3 and 2, respectively. In advanced glaucoma (stage III), most prominent increase of P100 amplitude of visual evoked potentials was demonstrated in group 2: amplitude of visual evoked potentials increased from 6.5 ± 0.2 to 8.1 ± 0.2 mcV, latency decreased from 87.5 ± 2.3 to 80.1 ± 2.1 ms. Maximal improvement of ocular circulation (increase of systolic blood velocity from 9.2 ± 0.72 to 11.2 ± 0.6 cm/s) and decrease of resistance index (from 0.84 ± 0.04 to 0.66 ± 0.03) was found in patients with stage III glaucoma in the group 3. 

Conclusion: Use of different methods of magnetic therapy especially in combination with electrostimulation activates ocular hemodynamics and stimulates bioelectric activity of visual cortex and may prevent visual functions impairment in glaucoma.

About the authors

T. G. Kamenskikh

Saratov State Medical University named after V.I. Razumovsky

Author for correspondence.
Email: kamtanvan@mail.ru

MD, PhD, the Head of the Eye Diseases Department

Russian Federation

E. V. Veselova

Saratov State Medical University named after V.I. Razumovsky

Email: fake@neicon.ru

Assistant Professor, Eye Diseases Department

Russian Federation

I. D. Kamenskikh

Saratov State Medical University named after V.I. Razumovsky

Email: fake@neicon.ru

PhD student, Eye Diseases Department

Russian Federation

References

  1. Нестеров АП. Первичная глаукома. М.: Медицина; 1995. 255 с. (Nesterov AP. Primary glaucoma. Moscow: Meditsina; 1995. 255 p. Russian).
  2. Егоров ЕА, Астахов ЮС, Щуко АГ, ред. Национальное руководство по глаукоме. М.: ГЭОТАР-Медиа; 2011. 279 с. (Egorov EA, Astakhov YuS, Shchuko AG, editors. Glaucoma: national guidance. Moscow: GEOTAR-Media; 2011. 279 p. Russian).
  3. Егоров ЕА, Тагирова СБ, Алябьева ЖЮ. Роль сосудистого фактора в патогенезе глаукоматозной оптической нейропатии. Клиническая офтальмология. 2002;(2):61–5. Egorov EA, Tagirova SB, Alyab’eva ZhYu. [The role of vascular factor in the pathogenesis of glaucomatous optical neuropathy]. Klinicheskaya oftal’mologiya. 2002;(2):61–5. Russian).
  4. Астахов ЮС, Акопов ЕЛ, Нефедова ДМ. Сосудистые факторы риска развития первичной открытоугольной глаукомы. Клиническая офтальмология. 2008;(2):68–9. (Astakhov YuS, Akopov EL, Nefedova DM. [Vascular risk factors in primary open angle glaucoma]. Klinicheskaya oftal’mologiya. 2008;(2):68–9. Russian).
  5. Пономаренко ГН. Общая физиотерапия: Учебник для студентов медицинских ВУЗов. М.: ГЭОТАР-Медиа; 2012. 420 с. (Ponomarenko GN. General physiotherapy. Moscow: GEOTAR-Media; 2012. 420 p. Russian).
  6. Neufeld AH. Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. Surv Ophthalmol. 1999;43 Suppl 1:S129–35.
  7. O’Brien C, Saxton V, Crick RP, Meire H. Doppler carotid artery studies in asymmetric glaucoma. Eye (Lond). 1992;6 (Pt 3):273–6.
  8. Orgul S, Flammer J. Interocular visual-field and intraocular-pressure asymmetries in normaltension-glaucoma. Eur J Ophthalmol.
  9. ;4(4):199–201.
  10. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987;327(6122):524–6.
  11. Pearson PJ, Schaff HV, Vanhoutte PM. Longterm impairment of endothelium-dependent relaxations to aggregating platelets after reperfusion injury in canine coronary arteries. Circulation. 1990;81(6):1921–7.
  12. Phelps CD, Corbett JJ. Migraine and low-tension glaucoma. A case-control study. Invest Ophthalmol Vis Sci. 1985;26(8):1105–8.
  13. Plange N, Remky A, Arend O. Absolute filling defects of the optic disc in fluorescein angiograms in glaucoma – a retrospective clinical study. Klin Monbl Augenheilkd. 2001;218(4):214–21.
  14. Pillunat LE, Stodtmeister R, Wilmanns I. Pressure compliance of the optic nerve head in low tension glaucoma. Br J Ophthalmol. 1987;71(3): 181–7.
  15. Trope GE, Salinas RG, Glynn M. Blood viscosity in primary open-angle glaucoma. Can J Ophthalmol. 1987;22(4):202–4.
  16. Weinreb RN. Why study the ocular microcirculation in glaucoma? J Glaucoma. 1992;1:145–7.
  17. Каменских ТГ, Райгородский ЮМ, Мышкина ЕЮ, Гусева МС. Цветоритмотерапия в коррекции психосоматических нарушений у больных с хронической офтальмопатологией. Окулист. 2007;(6):22–3. (Kamenskikh TG, Raygorodskiy YuM, Myshkina EYu, Guseva MS. [Color rhythm therapy in the correction of psychosomatic disorders in patients with chronic ophthalmopathy]. Okulist. 2007;(6):22–3. Russian).

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2015 Kamenskikh T.G., Veselova E.V., Kamenskikh I.D.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies