OSTEOGENESIS IMPERFECTA AND PREGNANCY: PROBLEMS EVOLVING BY THE TIME OF DELIVERY

Cover Page


Cite item

Abstract

The article describes a case of pregnancy in a patient with osteogenesis imperfecta. It is of note that both local and foreign medicine this disorder is a contraindication to pregnancy due to a high risk of maternal and fetal complications. The authors review literature on pre-pregnancy planning and preparation, pregnancy management, types of deliveries and approaches to anesthesia in female patients with osteogenesis imperfecta. Special attention is paid to anesthesiological complications during delivery, ways of their management and correction. Due to a high inheritance rate of this disorder, genetic consulting and extracorporeal fertilization methods are of great importance.

About the authors

S. R. Mravyan

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Author for correspondence.
Email: fake@neicon.ru

MD, PhD, Leading Research Fellow, Head of Therapeutic Group

Russian Federation

I. O. Shuginin

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

MD, PhD, Leading Research Fellow, Observational Obstetric Department

Russian Federation

S. V. Novikova

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

MD, PhD, Head of Observational Obstetric Department

Russian Federation

E. Yu. Upryamova

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

Junior Research Fellow, Department of Anesthesiology and Intensive Care

Russian Federation

I. I. Bocharova

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

MD, PhD, Leading Research Fellow, Department of Neonatology

Russian Federation

L. A. Zhuchenko

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

MD, PhD, Professor, Head of Department of Medical Genetics

Russian Federation

References

  1. Byers PH, Steiner RD. Osteogenesis imperfecta. Annu Rev Med. 1992;43:269–82.
  2. Gambling DR, Dougkas MJ, McKay RSF, editors. Obstetric anesthesia and uncommon disorder. 2nd edition. New York: Cambridge University Press; 2008. 445 p.
  3. Feng ZY, Chen Q, Shi CY, Wen HW, Ma K, Yang HX. A type IV osteogenesis imperfecta family and pregnancy: a case report and literature review. Chin Med J (Engl). 2012;125(7):1358–60.
  4. Sharma A, George L, Erskin K. Osteogenesis imperfecta in pregnancy: two case reports and review of literature. Obstet Gynecol Surv. 2001;56(9):563–6.
  5. Krishnamoorthy U, Vausse S, Donnai P. Management of pregnancy complicated by maternal osteogenesis imperfecta. Report of a case with uterine rupture. J Obstet Gynaecol. 2002;22(3):316.
  6. Di Lieto A, Pollio F, De Falco M, Iannotti F, Mascolo M, Somma P, Staibano S. Collagen content and growth factor immunoexpression in uterine lower segment of type IA osteogenesis imperfecta: Relationship with recurrent uterine rupture in pregnancy. Am J Obstet Gynecol. 2003;189(2):594–600.
  7. Приказ Минздравсоцразвития № 736 от 05.12.07 «Перечень медицинских показаний к прерыванию беременности». М.; 2007. (The Decree of the Ministry of Health and Social Development No. 736 from 05.12.07 “The List of Medical Indications to Termination of a Pregnancy”. Moscow; 2007. Russian).
  8. Lyra TG, Pinto VA, Ivo FA, Nascimento Jdos S. Osteogenesis imperfecta in pregnancy. Case report. Rev Bras Anestesiol. 2010;60(3): 321–4.
  9. Cubert R, Cheng EY, Mack S, Pepin MG, Byers PH. Osteogenesis imperfecta: mode of delivery and neonatal outcome. Obstet Gynecol. 2001;97(1):66–9.
  10. Anderer G, Hellmeyer L, Hadji P. Clinical management of a pregnant patient with type I osteogenesis imperfecta using quantitative ultrasonometry – a case report. Ultraschall Med. 2008;29(2):201–4.
  11. Chen CP, Lin SP, Su YN, Huang JP, Chern SR, Su JW, Wang W. Uncomplicated vaginal delivery in two consecutive pregnancies carried to term in a woman with osteogenesis imperfecta type I and bisphosphonate treatment before conception. Taiwan J Obstet Gynecol. 2012;51(2):305–7.
  12. Vogel TM, Ratner EF, Thomas RC Jr, Chitkara U. Pregnancy complicated by severe osteogenesis imperfecta: a report of two cases. Anesth Analg. 2002;94(5):1315–7.
  13. Yeo ST, Paech MJ. Regional anaesthesia for multiple caesarean sections in a parturient with osteogenesis imperfecta. Int J Obstet Anesth. 1999;8(4):284–7.
  14. Aly EE, Harris P. Spinal anesthesia in an obese patient with osteogenesis imperfecta. Can J Anaesth. 2003;50(4):421–2.
  15. Porsborg P, Astrup G, Bendixen D, Lund AM, Ording H. Osteogenesis imperfecta and malignant hyperthermia. Is there a relationship? Anaesthesia. 1996;51(9):863–5.
  16. Djokanovic N, Klieger-Grossmann C, Koren G. Does treatment with bisphosphonates endanger the human pregnancy? J Obstet Gynaecol Can. 2008;30(12):1146–8.
  17. Mastaglia SR, Watman NP, Oliveri B. Intravenous bisphosphonate treatment and pregnancy: its effects on mother and infant
  18. bone health. Osteoporos Int. 2010;21(11): 1959–62.

Copyright (c) 2015 Mravyan S.R., Shuginin I.O., Novikova S.V., Upryamova E.Y., Bocharova I.I., Zhuchenko L.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies