THE EXPERIENCE OF THE USE OF SYNTHETIC PROSTHESES FOR TREATMENT OF SEVERE GENITAL PROLAPSE IN ELDERLY FEMALES

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Abstract

Background: Genital prolapse is one of the most difficult-to-solve problems of gynecology. Rates of relapse after surgical correction of this disorder amounts to 33–40%.

Aim: To analyze the use of alloplastic materials for correction of severe forms of ptosis and prolapse of internal genitals in the elderly.

Materials and methods: 228 females aged from 60 to 70 with genital prolapse grade III–IV (according to classification by Baden-Walker) were divided into 3 groups depending on the leading anatomical structure in the prolapse. In all patients, extraperitoneal colpopexy with a prolene mesh was performed, with additional perineal plastics, in 165 patients from Group 1 (mean age, 63 years) being an anterior plastics, in 47 patients from Group 2 (mean age, 65 years) – posterior, in 12 patients from Group 3 (mean age, 68 years) – total. Efficacy of surgery was assessed at 2 to 4 months according to degree of genital prolapse, absence of erosions of vaginal walls and absence of the alloplast shrinkage and/or displacement.

Results: Almost in 50% patients, a latent form of urine incontinence was diagnosed that required an urethropexy by a free synthetic loop through a transobturator approach. Frequency of intraoperational complications was low (n = 1). Among post-operation complications, 60% patients from Groups 1 and 3 had urination disorders that resolved by days 4–5 after surgery with anti-inflammatory treatment and with the use of agents increasing the detrusor tone. Frequency of vaginal wall erosions and of a partial prosthesis expulsion was 4.2% each in Groups 1 and 2. There were no vaginal wall erosions in Group 3. Clinically insignificant partial shrinkage of the prolene mesh was noted in 4.5, 4.2 and 5.9% of cases in Groups 1, 2 and 3, respectively. After the surgical correction, in 100% of patients from Groups 1 and 3 and in 70.6% of patients from Group 2 their genital prolapse was assessed as having grade I according to Baden-Walker, and in 29.4% of patients from Group 2, as grade II. However, there were many cases of prolapse progression of the contralateral vaginal wall: in 72 (44%) of patients in Group 1 and in 4 (23,5%) in Group 2, that in some cases (18,4%) necessitated the surgery to be repeated.

Conclusion: The use of prolene mesh for extraperitoneal strengthening of the pelvic fundus in the elderly is an effective way of treatment. With strict adherence to proper surgical technique it is associated with a minimal number of complications that are mainly easily eliminated.

About the authors

M. V. Mgeliashvili

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Author for correspondence.
Email: fake@neicon.ru

PhD, Senior Research Fellow, Department of Gynecology

Russian Federation

S. N. Buyanova

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

MD, PhD, Professor, Honored Physician of the Russian Federation, Head of the Department of Gynecology

Russian Federation

T. B. Marchenko

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: marckela@gmail.com

Postgraduate Student, Department of Gynecology

Russian Federation

I. D. Rizhinashvili

Moscow Regional Scientific Research Institute for Obstetrics and Gynecology

Email: fake@neicon.ru

PhD, Senior Research Fellow, Consultative and Diagnostics Department

Russian Federation

References

  1. Буянова СН, Смольнова ТЮ, Иоселиани МН, Куликов ВФ. К патогенезу опущения и выпадения внутренних половых органов. Вестник Российской ассоциации акушеров-гинекологов. 1998;(1):77–9. (Buyanova SN, Smol'nova TYu, Ioseliani MN, Kulikov VF. [On the pathophysiology of ptosis and prolapse of internal genitals]. Vestnik Rossiyskoy assotsiatsii akusherov-ginekologov. 1998;(1):77–9. Russian).
  2. Буянова СН, Щукина НА, Журавлева АС. Эффективность использования сетчатых протезов при осложненных формах пролапса гениталий. Российский вестник акушера-гинеколога. 2009;(1):76–81. (Buyanova SN, Shchukina NA, Zhuravleva AS. [Efficiency of using mesh prostheses in complicated forms of genital prolapse]. Rossiyskiy vestnik akushera-ginekologa. 009;(1):76–81. Russian).
  3. Смольнова ТЮ, Буянова СН, Савельев СВ, Петрова ВД. Дисплазия соединительной ткани как одна из возможных причин недержания мочи у женщин с пролапсом гениталий. Урология. 2001;(2):25–30. (Smol'nova TYu, Buyanova SN, Savel'ev SV, Petrova VD. [Connective tissue dysplasia as one of potential reasons of urine incontinence in females with genital prolapse]. Urologiya. 2001;(2):25–30. Russian).
  4. Rinne KM, Kirkinen PP. What predisposes young women to genital prolapse? Eur J Obstet Gynecol Reprod Biol. 1999;84(1):23–5.
  5. Norton PA, Baker JE, Sharp HC, Warenski JC. Genitourinary prolapse and joint hypermobility in women. Obstet Gynecol. 1995;85(2): 225–8.
  6. Woodman PJ, Swift SE, O'Boyle AL, Valley MT, Bland DR, Kahn MA, Schaffer JI. Prevalence of severe pelvic organ prolapse in relation to job description and socioeconomic status: a multicenter cross-sectional study. Int Urogynecol J Pelvic Floor Dysfunct.
  7. ;17(4):340–5.
  8. Буянова СН, Савельев СВ, Петрова ВД, Шойбонов БЖ, Муравьева ТГ, Федоров АА, Лукашенко СЮ. Роль дисплазии соединительной ткани в патогенезе пролапса гениталий и недержания мочи. Российский вестник акушера-гинеколога. 2005;(5):19–23. (Buyanova SN, Savel'ev SV, Petrova VD, Shoybonov BZh, Murav'eva TG, Fedorov AA, Lukashenko SYu. [Role of connective tissue dysplasia in the pathogenesis of genital prolapse and urinary incontinence]. Rossiyskiy vestnik akusherainekologa. 2005;(5):19–23. Russian).
  9. Swift S, Woodman P, O'Boyle A, Kahn M, Valley M, Bland D, Wang W, Schaffer J. Pelvic Organ Support Study (POSST): the distribution, clinical definition, and epidemiologic condition of pelvic organ support defects. Am J Obstet Gynecol. 2005;192(3):795–806.
  10. Jha S, Moran PA. National survey on the management of prolapse in the UK. Neurourol Urodyn. 2007;26(3):325–31.
  11. Carey M, Higgs P, Goh J, Lim J, Leong A, Krause H, Cornish A. Vaginal repair with mesh versus colporrhaphy for prolapse: a randomized controlled trial. BJOG. 2009;116(10):1380–6.
  12. Martan A, Svabik K, Masata J, El-Haddad R, Pavlikova M. Correlation between stress urinary incontinence or urgency and anterior compartment defect before and after surgical treatment. Ceska Gynekol. 2010;75(2):118–25.
  13. Elmer C, Altman D, Engh ME, Axelsen S, Vayrynen T, Falconer C; Nordic Transvaginal Mesh Group. Trocar-guided transvaginal mesh repair of pelvic organ prolapse. Obstet Gynecol. 2009;113(1):117–26.
  14. Bai SW, Jeon MJ, Kim JY, Chung KA, Kim SK, Park KH. Relationship between stress urinary incontinence and pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2002;13(4):256–60.
  15. Rosenzweig BA, Pushkin S, Blumenfeld D, Bhatia NN. Prevalence of abnormal urodynamic test results in continent women with severe genitourinary prolapse. Obstet Gynecol. 1992;79(4):539–42.
  16. Al-Mandeel H, Ross S, Robert M, Milne J. Incidence of stress urinary incontinence following vaginal repair of pelvic organ prolapse in objectively continent women. Neurourol Urodyn. 2011;30(3):390–4.
  17. Johnson JD, Lamensdorf H, Hollander IN, Thurman AE. Use of transvaginal endosonography in the evaluation of women with stress urinary incontinence. J Urol. 1992;147(2): 421–5.

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Copyright (c) 2015 Mgeliashvili M.V., Buyanova S.N., Marchenko T.B., Rizhinashvili I.D.

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