POLYMORPHISM OF CHRONIC GLOMERULONEPHRITIS ASSOCIATION WITH ADPRT1 GENE VAL762ALA

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Abstract

Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-allele and Val/Val-genotype and lower in those with Ala-allele and Ala/Ala-genotype.

About the authors

E. S. Kamyshova

I.M. Sechenov First Moscow State Medical University

Author for correspondence.
Email: fake@neicon.ru
Russian Federation

M. Yu. Shvetsov

I.M. Sechenov First Moscow State Medical University

Email: fake@neicon.ru
Russian Federation

A. E. Shestakov

Clinicodiagnostic Laboratory FimedLab

Email: fake@neicon.ru
Russian Federation

I. M. Kutyrina

I.M. Sechenov First Moscow State Medical University

Email: fake@neicon.ru
Russian Federation

V. V. Nosikov

State Research Institute of Genetics and Selection of Industrial Microorganisms GNIIGENETIKA

Email: fake@neicon.ru
Russian Federation

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Copyright (c) 2014 Kamyshova E.S., Shvetsov M.Y., Shestakov A.E., Kutyrina I.M., Nosikov V.V.

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