Confocal laser endomicroscopy in the diagnosis of colorectal diseases: image interpretation criteria

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Abstract

Confocal laser endomicroscopy is a rapidly emerging area of gastroenterology that bridges endoscopy and histological examination. This newest technique has enabled endoscopists to assess the microstructure of gastrointestinal mucosa in vivo during the endoscopic procedure ("virtual biopsy"), and has stimulated growing interest to its application in clinical practice. During colonoscopy, the use of confocal laser endomicroscopy is justified for assessment of post-resection margins after excision of epithelial neoplasms, for differential diagnosis of polyps and assessment of the colon in patients with inflammatory bowel disorders. This article presents the interpretation criteria of confocal images in various colon diseases and the published data on the diagnostic value of the method.

About the authors

P. L. Shcherbakov

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow

Author for correspondence.
Email: petersh@rcpcm.org

Shcherbakov Petr L. – MD, PhD, Professor, Head of Hospital.
1A Malaya Pirogovskaya ul., Moscow, 119435, Russian Federation. Tel.: +7 (985) 764 54 43. E-mail: petersh@rcpcm.org
Russian Federation

M. V. Kirova

Moscow Clinical Research and Practical Center, Moscow Healthcare Department, Moscow

Email: fake@neicon.ru
Kirova Marina V. – MD, Senior Research Fellow Russian Federation

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Copyright (c) 2016 Shcherbakov P.L., Kirova M.V.

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