Email this article The etiology of viral respiratory infections in infants with community-acquired pneumonia
- Authors: Bogdanova A.V.1, Samodova O.V.1, Bugaeva O.S.1, Turabova A.L.2, Pyatlina T.V.2, Konyukhov A.Y.2, Volkova I.I.2, Danilogorskaya E.V.2
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Affiliations:
- Northern State Medical University
- Arkhangel'sk Regional Children's Clinical Hospital
- Issue: Vol 45, No 1 (2017)
- Pages: 2-7
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/468
- DOI: https://doi.org/10.18786/2072-0505-2017-45-1-2-7
- ID: 468
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Full Text
Abstract
Background: Community-acquired pneumonia can be caused by both bacterial and viral pathogens. The differential diagnosis based only on clinical data is not always feasible. The use of C-reactive protein (CRP) and procalcitonin might give some additional information for treatment decision-making.
Aim: To evaluate the structure and rates of viral isolation in community-acquired pneumonia in hospitalized infants and changes in CRP and procalcitonin levels.
Materials and methods: Seventy five infants at the age of up to 11 months and 29 days, who were hospitalized with community-acquired pneumonia confirmed by chest X-ray from March 2015 till February 2016, were included into the study. CRP and procalcitonin levels were measured. Detection of viruses in nasopharyngeal swabs was performed by a real-time polymerase chain reaction.
Results: Nucleic acids of respiratory viruses were isolated in 72% (54/75) of infants. The most common were respiratory syncytial virus (in 70.4%, 38/54) and human rhinovirus (in 16.6%, 9/54). Median of white blood cell count in pneumonia associated with respiratory viruses was 10.95 (9; 14.1)×109/L, CRP level, 1.95 (0.5; 7) mg/L, procalcitonin level, 0.087 (0.067; 0.17) ng/mL.
Conclusion: The study showed a high prevalence of respiratory viruses in community-acquired pneumonia in infants. There was no increase in CRP and procalcitonin levels in pneumonia associated with respiratory viruses.
About the authors
A. V. Bogdanova
Northern State Medical University
Author for correspondence.
Email: alessandra.bogdanova@yandex.ru
MD, Postgraduate Student, Chair of Infectious Diseases,
51 Troitskiy prospekt, Arkhangel'sk, 163000
Russian FederationO. V. Samodova
Northern State Medical University
Email: fake@neicon.ru
MD, PhD, Head of the Chair of Infectious Diseases,
51 Troitskiy prospekt, Arkhangel'sk, 163000
Russian FederationO. S. Bugaeva
Northern State Medical University
Email: fake@neicon.ru
Resident, Chair of Infectious Diseases,
51 Troitskiy prospekt, Arkhangel'sk, 163000
Russian FederationA. L. Turabova
Arkhangel'sk Regional Children's Clinical Hospital
Email: fake@neicon.ru
MD, Head of the Department of Clinical Laboratory Diagnostics,
7 Obvodnyy kanal prospekt, Arkhangel'sk, 163002
Russian FederationT. V. Pyatlina
Arkhangel'sk Regional Children's Clinical Hospital
Email: fake@neicon.ru
MD, Physician, Department of Clinical Laboratory Diagnostics,
7 Obvodnyy kanal prospekt, Arkhangel'sk, 163002
Russian FederationA. Yu. Konyukhov
Arkhangel'sk Regional Children's Clinical Hospital
Email: fake@neicon.ru
MD, Physician, Department of Infectious Diseases,
7 Obvodnyy kanal prospekt, Arkhangel'sk, 163002
Russian FederationI. I. Volkova
Arkhangel'sk Regional Children's Clinical Hospital
Email: fake@neicon.ru
MD, Head of the Department of Infectious Diseases,
7 Obvodnyy kanal prospekt, Arkhangel'sk, 163002
Russian FederationE. V. Danilogorskaya
Arkhangel'sk Regional Children's Clinical Hospital
Email: fake@neicon.ru
MD, Physician, Department of Infectious Diseases,
7 Obvodnyy kanal prospekt, Arkhangel'sk, 163002
Russian FederationReferences
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