Email this article Sedation with dexmedetomidine reduces the duration of delirium treatment in sufferers with severe concomitant trauma
- Authors: Bershadskiy F.F.1, Ulitkina O.N.1, Skripkin Y.V.1, Likhvantsev V.V.1
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Affiliations:
- Moscow Regional Research and Clinical Institute (MONIKI)
- Issue: Vol 45, No 8 (2017)
- Pages: 652-657
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/669
- DOI: https://doi.org/10.18786/2072-0505-2017-45-8-652-657
- ID: 669
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Abstract
Rationale: Delirium would deteriorate the outcomes and treatment results in the patients with severe concomitant trauma. Its treatment efficacy is especially relevant for such patients. Aim: To identify an optimal sedation strategy for delirium in the sufferers with severe concomitant trauma. Materials and methods: Sixty (60) patients with delirium that developed against the background of severe concomitant trauma were included into this randomized, retrospective-prospective study. One group of patients (n=30) was sedated with dexmedetomidine, the other one (n=30), with propofol. Results: In the group with dexmedetomidine sedation, the duration of delirium was 6 [5–6] days, whereas in the propofol group, 7 [6–8] days (p=0.003). The type of sedation was not associated with the severity of delirium, whose maximum ICDSC score was 7 [4–7] points in the propofol group and 6 [4–6] points in the dexmedetomidine group (p=0.32). Conclusion: Compared to propofol, dexmedetomidine may help to reduce the duration of treatment for non-specific delirium in severe concomitant trauma by 1 day.
Keywords
About the authors
F. F. Bershadskiy
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
MD, Research Fellow, Department of Anesthesiology and Intensive Care Russian Federation
O. N. Ulitkina
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
MD, Research Fellow, Department of Anesthesiology and Intensive Care Russian Federation
Yu. V. Skripkin
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
MD, PhD, Head of the Intensive Care Unit Russian Federation
V. V. Likhvantsev
Moscow Regional Research and Clinical Institute (MONIKI)
Author for correspondence.
Email: lik0704@gmail.com
MD, PhD, Professor, Head of the Department of Anesthesiology and Intensive Care Russian Federation
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