Email this article Wollfian tumor: a case report and a literature review
- Authors: Dubova E.A.1, Pavlov К.A.1, Lishchuk S.V.1, Tertychnyi A.S.2, Bakhvalova A.A.2, Bryunin D.V.2
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Affiliations:
- Russian State Research Center – Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency
- I.M. Sechenov First Moscow State Medical University
- Issue: Vol 46, No 4 (2018)
- Pages: 374-378
- Section: CLINICAL CASES
- URL: https://almclinmed.ru/jour/article/view/856
- DOI: https://doi.org/10.18786/2072-0505-2018-46-4-374-378
- ID: 856
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Abstract
Wolffian tumor is a rare neoplasm arising from mesonephric duct remnants. Not more than 100 cases of the disease have been described. The authors present their own clinical observation of the Wolffian tumor in a 43-year old female patient. Radiological examinations resulted in the suspicion of a subserous leiomyoma of the uterus; however, the surgery showed a mass arising from the fallopian tube wall. Histologically, there was a growing tumor within the fallopian tube wall with no mucosal lesions. The tumor consisted of myxomatous stroma with cribriform, solid and reticular areas composed of relatively monomorphic, mildly eosinophilic cells with monotonous nuclei and single mitoses. On immunohistochemistry, the tumor cells expressed vimentin, pan-cytokeratin, cytokeratin 7 and calretinin. This case illustrates that final verification and differential diagnosis of the tumor with other fallopian tube neoplasms, including malignancies, is only possible with an immunohistochemical study.
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About the authors
E. A. Dubova
Russian State Research Center – Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency
Author for correspondence.
Email: dubovaea@gmail.com
Elena A. Dubova – MD, PhD, Pathologist, Department of Pathology
46 Zhivopisnaya ul., Moscow, 123182
Russian FederationК. A. Pavlov
Russian State Research Center – Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency
Email: fake@neicon.ru
Konstantin A. Pavlov – MD, PhD, Pathologist, Department of Pathology
46 Zhivopisnaya ul., Moscow, 123182
Russian FederationS. V. Lishchuk
Russian State Research Center – Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency
Email: fake@neicon.ru
Sergey V. Lishchuk – MD, Head of Department of Pathology
46 Zhivopisnaya ul., Moscow, 123182
Russian FederationA. S. Tertychnyi
I.M. Sechenov First Moscow State Medical University
Email: fake@neicon.ru
Alexander S. Tertychnyi – MD, PhD, Professor, A.I. Strukov Department of Pathology
8/2 Trubetskaya ul., Moscow, 119991
Russian FederationA. A. Bakhvalova
I.M. Sechenov First Moscow State Medical University
Email: fake@neicon.ru
Alla A. Bakhvalova – MD, PhD, Gynecologist, Department of Obstetrics and Gynecology, V.F. Snegirev Clinic of Obstetrics and Gynecology
8/2 Trubetskaya ul., Moscow, 119991
Russian FederationD. V. Bryunin
I.M. Sechenov First Moscow State Medical University
Email: fake@neicon.ru
Dmitriy V. Bryunin – MD, PhD, Professor, Head of Department of Obstetrics and Gynecology, V.F. Snegirev Clinic of Obstetrics and Gynecology
8/2 Trubetskaya ul., Moscow, 119991
Russian FederationReferences
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