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Гепатоцеллюлярный рак и трансплантация печени: от хаоса к порядку

https://doi.org/10.18786/2072-0505-2018-46-6-552-559

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Аннотация

Подходы к  лечению пациентов с  гепатоцеллюлярным раком (ГЦР), развившимся на фоне заболевания печени, быстро меняются. Выбор терапевтического алгоритма осложняется также по причине множества существующих вариантов лечения и участия в процессе большого числа врачей самых разных специальностей. ГЦР независимо от этиологии следует в первую очередь рассматривать как хирургическую болезнь. Возможности хирургии, включая частичную резекцию и  трансплантацию печени, долго недооценивались и даже были сведены к  минимуму вследствие многочисленных исследований, результаты которых привели к  продвижению различных методов местно-регионарного и  системного лечения. Местно-регионарное лечение и хирургические вмешательства следует считать не конкурирующими, а  взаимодополняющими подходами к  лечению. Методы местно-регионарного лечения имеют значение только при невозможности проведения оперативного вмешательства. В контексте трансплантации они играют большую роль как способ уменьшения стадии опухоли, то есть приведения пациентов, которым может быть выполнена трансплантация, в соответствие с требуемыми критериями отбора. В будущем значимость системной терапии и трансплантации печени живого донора в лечении ГЦР, несомненно, будет повышаться.

Об авторах

Я. Лерут
Университетская клиника Св. Луки, Католический университет Лювена
Бельгия

Лерут Ян – MD, PhD, профессор.

1200, Брюссель, Авеню Гиппократа, 10



С. Езари
Аквильский университет
Италия

Езари Самуэле – MD, отделение биотехнологических и прикладных клинических наук.

67100, Коппито (Аквила), ул. Джованни Фальконе, 25



М. Фогенн
Университетская клиника Св. Луки, Католический университет Лювена
Бельгия

Фогенн Максим – MD, отделение абдоминальной хирургии и трансплантологии им. Т. Старзла.

1200, Брюссель, Авеню Гиппократа, 10



К. Акенин
Университетская клиника Св. Луки, Католический университет Лювена
Бельгия

Акенин Кевин – MD, отделение абдоминальной хирургии и трансплантологии им. Т. Старзла.

1200, Брюссель, Авеню Гиппократа, 10



К. Лай
Университет «Ла Сапиенца»
Италия

Лай Квирино – MD, PhD, отделение общей хирургии и трансплантации органов.

00185, Рим, площадь Альдо Моро, 5



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Для цитирования:


Лерут Я., Езари С., Фогенн М., Акенин К., Лай К. Гепатоцеллюлярный рак и трансплантация печени: от хаоса к порядку. Альманах клинической медицины. 2018;46(6):552-559. https://doi.org/10.18786/2072-0505-2018-46-6-552-559

For citation:


Lerut J., Iesari S., Foguenne M., Ackenin K., Lai Q. Hepatocellular cancer and liver transplantation: necessity to go from chaos to order. Almanac of Clinical Medicine. 2018;46(6):552-559. (In Russ.) https://doi.org/10.18786/2072-0505-2018-46-6-552-559

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ISSN 2072-0505 (Print)
ISSN 2587-9294 (Online)