Ultrasonography and fine-needle aspiration biopsy in the diagnosis of a cystic type of thyroid papillary cancer

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Abstract

Background: Cystic type of thyroid papillary carcinoma is a  rare independent disease of this organ. Its prevalence among papillary carcinomas is from 2.5 to 6%.

Aim: To identify ultrasonographic features of the cystic form of papillary carcinoma for the differential diagnosis of solitary liquid neoplasms of the thyroid and to elaborate an optimal technique for its fine-needle aspiration biopsy.

Materials and methods: We retrospectively analyzed the data on the diagnosis and treatment of 29  patients with the cystic type of thyroid papillary carcinoma (26  women, 3  men, mean age 52  years). The instrumental diagnosis was based on a  comprehensive ultrasonography and fine-needle aspiration biopsy.

Results: We identified the following ultrasonographic characteristics of “potentially malignant” cystic nodules of the thyroid: the wall thickness of  2 to  3  mm with marginal tissue components of various size (from 10 mm to 3 cm in diameter) and microcalcinates; presence of focal blood supply by color Doppler mapping; homogeneity and low echogenicity of the liquid component. Conclusion: The right interpretation of the ultrasonographic results and adequately performed fine-needle aspiration biopsy help to verify the diagnosis of thyroid carcinoma and to avoid mistake in the treatment of this patient category. 

About the authors

T. A. Britvin

Moscow Regional Research and Clinical Institute (MONIKI)

Email: fake@neicon.ru

Timur A. Britvin – MD, PhD, Professor, Head of the Department of Surgical Endocrinology,

61/2 Shchepkina ul., Moscow, 129110

Russian Federation

E. V. Bondarenko

Moscow Regional Research and Clinical Institute (MONIKI)

Author for correspondence.
Email: ekaterinabondarenko@inbox.ru

Ekaterina V. Bondarenko – Research Fellow, Department of Pathological Anatomy,

61/2–13 Shchepkina ul., Moscow, 129110

+7 (916) 177 99 97

Russian Federation

V. O. Bondarenko

Russian Medical Academy of Continuous Professional Education

Email: fake@neicon.ru

Vladimir O. Bondarenko – MD, PhD, Professor, Chair of Endocrinology and Diabetology, Therapeutic Faculty,

2/1–1 Barrikadnaya ul., Moscow, 125993

Russian Federation

T. Yu. Demidova

Pirogov Russian National Research Medical University (RNRMU)

Email: fake@neicon.ru

Tatiyana Yu. Demidova – MD, PhD, Professor, Head of the Chair of Endocrinology, Faculty of Medicine,

1 Ostrovityanova ul., Moscow, 117997

Russian Federation

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Copyright (c) 2019 Britvin T.A., Bondarenko E.V., Bondarenko V.O., Demidova T.Y.

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